Hepatectomy is a critical surgical procedure that involves the removal of a portion of the liver. Depending on the condition and location of the liver issue, either a right hepatectomy or a left hepatectomy is performed. These surgeries are most commonly undertaken to treat liver cancer, metastatic tumors, benign liver growths, or to remove damaged liver tissue due to trauma or infection. In fact, the benefits of right or left hepatectomy often outweigh the risks, particularly when performed in experienced surgical centers.
Though the idea of surgically removing part of an organ as vital as the liver may seem intimidating, modern surgical techniques and improved post-operative care have made hepatectomy both safe and effective.
Benefits of Right or Left Hepatectomy
The liver is divided into eight segments based on its blood supply and bile drainage system. These segments are grouped into lobes:
- The right lobe comprises segments 5 to 8.
- The left lobe includes segments 2 to 4 (segment 1, the caudate lobe, is sometimes treated separately).
- Right Hepatectomy :- A right hepatectomy involves the removal of the right lobe of the liver. It is generally indicated when tumors or lesions are located in the right side, or when there is a disease process that predominantly affects this portion.
- Left Hepatectomy :- A left hepatectomy, on the other hand, removes the left lobe. It’s performed when abnormalities are confined to that side, such as benign tumors, focal nodular hyperplasia, or metastatic deposits.Both surgeries are considered major hepatic resections, but the human liver has a remarkable regenerative capacity, which makes these procedures viable with proper medical planning.
Major Benefits of Right or Left Hepatectomy
- Removal of Liver Tumors :- One of the primary benefits of hepatectomy is the complete surgical removal of liver tumors. This includes:
- Hepatocellular carcinoma (HCC)
- Cholangiocarcinoma (bile duct cancer)
- Metastatic colorectal cancer
- Benign tumors like hemangiomas or adenomas causing symptoms
When tumors are confined to one lobe, a right or left hepatectomy allows surgeons to completely excise cancerous tissue, which may offer the best chance for long-term survival or even cure.
- Improved Liver Function in Select Conditions :- In certain liver conditions such as fibrosis, focal infection, or hydatid cysts, removing the diseased portion can help preserve or enhance the functionality of the remaining liver.For example, in conditions where one lobe is significantly fibrotic or damaged due to chronic inflammation, resection of that lobe helps the healthier part of the liver function more efficiently.
- Enhances Eligibility for Liver Transplantation or Downstaging :- In some cases, a hepatectomy serves as a bridge to transplantation or as a downstaging tool. For example:
- In patients awaiting liver transplantation, removing a part of the liver affected by a tumor may buy valuable time and prevent disease progression.
- In other cases, reducing tumor burden can make patients eligible for future curative treatments or systemic therapy.
This strategic surgical approach enhances treatment flexibility and may extend patient survival significantly.
- Preservation of Healthy Liver Tissue :- One of the reasons why segmental or lobar hepatectomy is preferred over total resection is that it allows for preservation of healthy liver tissue. This approach reduces surgical risk, shortens recovery time, and ensures that liver function remains optimal post-surgery.Surgeons often use advanced imaging (CT, MRI, intraoperative ultrasound) and 3D modeling to map the exact extent of disease. This precision planning ensures that only the affected lobe is removed, minimizing unnecessary loss of healthy tissue.
- Minimally Invasive Options Available :- While hepatectomy was traditionally performed via open surgery, laparoscopic and robotic-assisted techniques have now become viable in many cases, especially for left hepatectomy.Benefits of minimally invasive hepatectomy include:
- Smaller incisions
- Less post-operative pain
- Faster return to daily activities
- Lower risk of wound infection
Patients undergoing laparoscopic left hepatectomy, in particular, often report quicker recovery times compared to traditional surgery.
- Reduced Risk of Tumor Recurrence :- Complete resection of cancerous liver tissue during a right or left hepatectomy significantly reduces the risk of local recurrence. In cancers like hepatocellular carcinoma or liver metastases from colorectal cancer, surgical resection offers superior outcomes compared to non-surgical treatment.In carefully selected patients, 5-year survival rates after hepatectomy for liver cancer can reach up to 50–60%, depending on tumor type and underlying liver function.
- Improved Quality of Life :- Patients suffering from large or symptomatic liver lesions often experience discomfort, abdominal fullness, or other digestive symptoms. A right or left hepatectomy can provide significant symptom relief, resulting in a better quality of life.Additionally, for patients whose tumors secrete hormones or affect systemic function (such as insulinoma metastases or neuroendocrine tumors), removal of the affected liver lobe can alleviate systemic symptoms, improving physical and emotional well-being.
- Supports Liver Regeneration :- Perhaps one of the most unique advantages of hepatectomy is the liver’s natural regenerative ability. The remaining liver tissue undergoes hypertrophy (growth in size) to compensate for the removed portion, often restoring full liver volume within weeks.This regenerative feature makes partial liver resection not only feasible but also sustainable for long-term health, especially when combined with liver-boosting nutrition and medical care.
Conclusion
Right and left hepatectomy surgeries are among the most effective treatments for various liver diseases, especially when localized to a specific lobe. With the advancements in surgical techniques, imaging technologies, and perioperative care, patients today have better outcomes and faster recovery than ever before.
Choosing between right or left hepatectomy depends on the location of the disease, extent of liver involvement, and overall liver function. However, the benefits are clear from improved survival in cancer cases to restored liver functionality in benign diseases, these surgical interventions offer hope, healing, and longevity.